Schedule

The course meets Tuesdays and Thursday 9-10:30 am in Broad 100.


TA office hours are Mondays 2:30–4 pm in B125 Kerckhoff (if too many people, then in B136 Kerckhoff) and Wednesdays 2:30-4 pm in B123 Kerckhoff.


Instructor office hours are Fridays 2-3 pm in B123 Kerckhoff.


The due dates and schedule below are tentative and subject to change.

Due dates

All due times are 9 AM PST, unless otherwise specified.

Th 01/04
Homework 0
Th 01/11
Homework 1
Th 01/18
Homework 2
Th 01/25
Homework 3
Th 02/01
Homework 4
Tu 02/06
Midterm exam
Th 02/15
Homework 5
Th 02/22
Homework 6
Th 02/29
Homework 7
Th 03/07
Homework 8
Th 03/14
Final exam

Lecture schedule

Below is an approximate lecture schedule. I say "approximate" because some topics will be covered in less that one lecture and others in more. Listed with many of the lectures are suggested readings from Kuriyan, Konforti, and Wemmer (KKW), Wittrup, Tidor, Hackel, and Sarkar (WTHS), and occasionally Dill and Bromberg (DB).


You may download the lecture notes. They are in draft form and are continually updated throughout the term. There is no guarantee that typed versions of the notes will be available throughout the whole course.


Th 01/04
Why study biophysical chemistry?
Tu 01/09
Mass action kinetics
  • KKW sections 15.1–15.10
  • WTHS sections 1.5.3, 2.1, and 3.2
Th 01/11
Analytical solutions of chemical kinetic equations
Numerical solution of chemical kinetic equations
Tu 01/16
Enzymatic catalysis
  • KKW chapter 16
  • WTHS sections 4.1–4.3.3
Th 01/18
Measurement of chemical rates
  • KKW chapter 15.15–15.21
  • WTHS sections 2.6, 2.7, and 3.4
Tu 01/23
Catch-up
  • If you are interested in bioreactors, read WTHS section 7.3
Th 01/25
Mathematical preliminaries for thermodynamics: Probability, Lagrange multipliers,and others
  • KKW chapter 7.1–7.14
Tu 01/30
Entropy as ignorance (and math review of Lagrange multipliers)
  • KKW chapter 7.15–7.19
  • DB pages 66–72
Th 02/01
The Boltzmann distribution
  • KKW section 6.10
  • DB chapter 5
Tu 02/06
Midterm exam
Th 02/08
Thermodynamic potentials
  • KKW chapters 8C and 9
  • DB chapters 6 and 8
Tu 02/13
Thermodynamic relations
  • KKW chapter 10.1–10.11
  • DB chapter 15
Th 02/15
Thermodynamic stability
  • KKW chapter 12A, section 12.23
  • WTHS sections 3.1, 3.7, and 3.8
Tu 02/20
Solution thermodynamics I
  • KKW chapter 14
  • WTHS section 3.3
Th 02/22
Solution thermodynamics II
  • KKW chapter 17A
Tu 02/27
Electrochemistry
  • KKW chapters 17B and 17C
  • WTHS sections 3.3, 8.1, and 8.2
Th 03/01
Transport by thermal diffusion
  • KKW chapter 18C
Tu 03/06
Analytical methods
  • KKW chapter 10D, 18A
Th 03/08
Course wrap-up